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Scientist or Senior Scientist, high-throughput screening, fragment-based drug discovery | Small Mole
University of California, San Francisco
San Francisco, California
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Path 1: Research Assistant - Synthesis and Application of New Drug Delivery Systems based on Iron-oxide and Nobel metals Nanoparticles
RESEARCH PROJECT TITLE: SYNTHESIS AND APPLICATION OF NEW DRUG DELIVERY SYSTEMS BASED ON IRON-OXIDE AND NOBEL METALS NANOPARTICLESFACULTY NAME & TITLE: ALI TRABOLSI, ASSISTANT PROFESSOR IN CHEMISTRY, MAZIN MAGZOUB, ASSISTANT PROFESSOR IN BIOLOGY RESEARCH PROJECT DESCRIPTION:The focus of the project is on the development of a novel therapeutic nanoplatform, Targeted Chemotherapeutic Nanoparticles (T-CNPs), for the diagnosis and treatment cancer. The T-CNPs will be composed of iron oxide NPs that are: i) functionalized with water-soluble organic nanocontainers, for the encapsulation of a combination of hydrophobic and/or hydrophilic drugs that can act synergistically; ii) conjugated to cell-penetrating peptides (CPPs) – either d
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