About Northeastern: Founded in 1898, Northeastern is a global research university and a world leader in experiential learning. The same commitment to connecting with the world drives our use-inspired research enterprise. The university offers a comprehensive range of undergraduate and graduate programs leading to degrees through the doctorate in nine colleges and schools. Our campuses in Charlotte, N.C., San Francisco, Seattle, and Toronto are regional platforms for undergraduate and graduate learning and collaborative research. Northeastern pursues advanced research in security and materials at the Innovation Campus in Burlington, Massachusetts, and in coastal sustainability at the Marine Science Center in Nahant, Massachusetts.
About the Opportunity: Our laboratory studies the pharmacology of brain neuromodulators in the context of development of novel therapeutic interventions for neuropsychiatric illnesses. Presently, our primary focus is on subtypes of G-protein coupled receptors, such as dopamine, muscarinic, and cannabinoid receptors and their coupling to distinct effector and transduction pathways.
We seek a highly motivated Postdoctoral Fellow with expertise in brain slice electrophysiology and an interest in molecular pharmacology. In addition to work in brain slices, the successful candidate will receive training in cultured cell systems using novel approaches such as bioluminescence resonance energy transfer (BRET) and biosensor-based functional measurements to achieve more comprehensive understanding of receptor biology.
The laboratory is currently involved in collaborations with medicinal chemists, computational biophysicists, electrophysiologists, and rodent behaviorists at the NIH, complementing our efforts in molecular pharmacology and brain slice electrophysiology.
Responsibilities: Research work - The successful candidate will be responsible for experimental work from start to finish (i.e., help design, execute, analyze, summarize experiments, and foresee potential problems).
Reading/Writing - Keep up-to-date with current literature in relevant research fields, generate new research ideas, provide presentations and data summaries, and assist in writing research papers, and grant proposals.
Lab management / training personnel - Carry out general laboratory upkeep involving ordering supplies and updating inventories, organizing record-keeping, and in assisting graduate students with experimental techniques.
Scientific meetings - Participate regular laboratory and departmental meetings as well as seminars on and off campus. The successful candidate will also have opportunities to present data from the laboratory at national conferences.
Qualifications: The successful candidate must have a Ph.D. or equivalent in neurobiology, pharmacology, or other relevant field, with training emphasis on rodent brain slice electrophysiology. A candidate with a strong desire to learn molecular pharmacology and biosensor-based assays as a part of training will receive strong consideration.
Responsibilities related to electrophysiology work include assistance with maintenance of transgenic mouse colonies, stereotactic surgical (e.g., viral injection into selective brain regions) procedures in mice, and performing field, cell-attached, and whole-cell electrophysiological recordings in vitro, as well as in the analysis and presentation of these data. Specific responsibilities related to newly acquired techniques (e.g., molecular pharmacology and biosensor work) will be discussed once the training plan is agreed upon.
Preferred Qualifications: Salary Grade: 10
The successful Postdoctoral Fellow candidate will conduct research under the guidance of the PI and will work with other members of the laboratory and collaborators to ensure steady progress and completion of projects. The Fellow's career development will be strongly supported with anticipation that the fellow will pursue a career in academic, industrial, or government research. In addition, the successful candidate will have opportunities to supervise one or two master's students in the laboratory. Please reach out to Dr. Hideaki Yano at firstname.lastname@example.org with any questions.
Northeastern University is an equal opportunity employer, seeking to recruit and support a broadly diverse community of faculty and staff. Northeastern values and celebrates diversity in all its forms and strives to foster an inclusive culture built on respect that affirms inter-group relations and builds cohesion.
All qualified applicants are encouraged to apply and will receive consideration for employment without regard to race, religion, color, national origin, age, sex, sexual orientation, disability status, or any other characteristic protected by applicable law.
Founded in 1898, Northeastern University is a private research university located in the heart of Boston. Northeastern is a leader in worldwide experiential learning, urban engagement, and interdisciplinary research that meets global and societal needs. Our broad mix of experience-based education programs?our signature cooperative education program, as well as student research, service learning, and global learning?build the connections that enable students to transform their lives. The University offers a comprehensive range of undergraduate and graduate programs leading to degrees through the doctorate in nine colleges and schools.