Cures Start Here. At Fred Hutchinson Cancer Research Center, home to three Nobel laureates, interdisciplinary teams of world-renowned scientists seek new and innovative ways to prevent, diagnose and treat cancer, HIV/AIDS and other life-threatening diseases. Fred Hutchs pioneering work in bone marrow transplantation led to the development of immunotherapy, which harnesses the power of the immune system to treat cancer. An independent, nonprofit research institute based in Seattle, Fred Hutch houses the nations first cancer prevention research program, as well as the clinical coordinating center of the Womens Health Initiative and the international headquarters of the HIV Vaccine Trials Network. Careers Start Here.
The Paulovich Lab at Fred Hutch is an interdisciplinary team whose mission is to develop and implement tools for protein quantification to enable precision medicine (patient selection and identification of novel therapeutic targets). The lab has a major focus on mass spectrometry, especially multiple reaction monitoring. Our group is highly collaborative, participating in national and international consortia in which teams of scientists, statisticians, and clinicians work together to solve clinical or biological problems to impact human health.
This is a terrific opportunity for a highly motivated, interactive, Protein or Analytical Chemist to join our translational proteomics team to help drive translational projects forward towards clinical applications by performing proteomic experiments and participating in the analysis and interpretation of results.
Process proteomic samples for LC-MS analysis (e.g., protein extraction, fractionation, immuno-depletion, trypsin digestion, alkylation, reduction, etc.)
Perform HPLC separations and maintain HPLC instruments
Work with antibodies (immunoaffinity purification, immobilization on solid supports, screening hybridomas for mass spectrometry)
Generate mass spectrometry (MS)-based proteomics data and maintain MS instruments
Contribute to the analysis of proteomic (mass spectrometry) datasets
Collaborate effectively with an interdisciplinary team spanning expertise in biology, analytical chemistry, and statistics
Collaborate with others to develop new methods and tools that support research objectives
Maintain research results files and databases
Assist with written progress reports and development of standard operating protocols (SOP)
Assist with writing scientific manuscripts for peer-reviewed journals
Ph.D. degree in Protein Chemistry, Analytical Chemistry, Biochemistry, or related discipline and 3+ years of experience is required
The work is rigorously quantitative, and exquisite attention to detail and the ability to adhere to standard operating protocols (SOP) and maintaining records are critical
The position includes drafting manuscripts for publication and, thus a demonstrated track record of first author peer-reviewed journal publications, as well as excellent written communication skills are required.
The position includes giving oral presentations at local meetings, on consortium teleconferences, and at national and international meetings; thus excellenT oral communication skills are required.
Previous experience in a CLIA or clinical lab environment is a plus
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At Fred Hutchinson Cancer Research Center, teams of world-renowned scientists and humanitarians work together to prevent, diagnose and treat cancer, HIV/AIDS and other diseases. Researchers are discovering new ways to detect cancers earlier, improve treatments, and learn how to prevent cancers from growing. Although Fred Hutchinson opened its doors in 1975, its history began about 20 years before that. In 1962 Fred Hutchinson envisioned a center devoted to studying cancer, a disease that took his brother’s life. Today Fred Hutchinson is contributing to the next waves of breakthrough treatments and prevention strategies. Fred Hutchinson collaborates with the Seattle Cancer Alliance, the National Cancer Institute, and the University of Washington.