Molecular Biology and Protein Chemist Assistant, Associate, or Full Specialist Series Gross Lab, Department of Pharmaceutical Chemistry University of California, San Francisco
The Laboratory of Professor John Gross in the Department of Pharmaceutical Chemistry has an open position for a molecular biologist/protein biochemist. The Gross Lab’s research is focused on reconstituting and resolving host pathogen conflicts. We employ advanced tools for this work ranging from X-ray crystallography to EM, which require complexes to be purified from endogenous sources or reconstituted from recombinant purified components. The successful candidate will work within the UCSF HARC center to express and purify target complexes using a variety of eukaryotic expression systems. Primary methods for expression of target proteins will be carried out using mammalian cell culture in suspension. The candidate will have the opportunity to work with antigen binding fragments (Fabs), which have the potential to be used in HIV immunotherapy. Accordingly, the candidate will have experience with mammalian cell culture and molecular biology in addition to basic techniques utilized modern protein chemistry.
Specialists appointed at the Assistant or Associate rank must have a minimum of a master’s degree (or equivalent) in life sciences field or at least five years of research experience
Specialists appointed at the Full rank must possess a terminal degree (or equivalent degree) in life sciences field or at least ten years of research experience
Experience in mammalian cell culture, molecular biology and/or protein chemistry
Interest and experience working in a team research environment
Strong written and communication skills
PhD (or equivalent) in life sciences or related field
Expertise working with a variety of eukaryotic cell lines
Molecular biology, mammalian cell culture and techniques, qPCR, immunoblot, in vitro transcription and translation, microscopy, plasmid vector construction, DNA and RNA sequencing
Experience with protein purification on small and preparative scale
Experience with enzyme biochemistry and quantitative analysis of activity
Salary will be commensurate with the applicant’s experience and training.
UCSF seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment of diversity and excellence. The University of California is an Equal Opportunity/Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age or protected veteran status.
Applicants should submit a brief cover letter and a curriculum vitae. Please apply online and submit these documents along with the contact information for at least two references to:https://aprecruit.ucsf.edu/apply/JPF01966
Internal Number: JPF01966
About University of California, San Francisco
The University of California, San Francisco (UCSF) is a leading university dedicated to promoting health worldwide through advanced biomedical research, graduate-level education in the life sciences and health professions, and high-quality patient care. It is the only UC campus in the 10-campus system dedicated exclusively to the health sciences.